CEACAM8
CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8) is a protein that in humans is encoded by the CEACAM8 gene. It is a member of the carcinoembryonic antigen (CEA) gene family.
Function[edit | edit source]
CEACAM8 is a cell adhesion molecule and a member of the immunoglobulin superfamily. It is expressed on the surface of granulocytes and plays a role in inflammation and immune response. It is also involved in the process of cell adhesion and in the activation of granulocytes.
Clinical significance[edit | edit source]
Alterations in the expression of CEACAM8 have been associated with various diseases, including cancer, inflammatory diseases, and infectious diseases. It has been suggested as a potential biomarker for these conditions.
Structure[edit | edit source]
The CEACAM8 protein is a type I transmembrane protein that consists of an extracellular region, a single transmembrane region, and a short cytoplasmic tail. The extracellular region contains three immunoglobulin-like domains.
Interactions[edit | edit source]
CEACAM8 has been shown to interact with other members of the CEA family, including CEACAM1, CEACAM3, and CEACAM6.
See also[edit | edit source]
References[edit | edit source]
 | This protein-related article is a stub. You can help WikiMD by expanding it. |
 | This medical article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
