CEACAM8

CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8) is a protein that in humans is encoded by the CEACAM8 gene. It is a member of the carcinoembryonic antigen (CEA) gene family.

Function[edit]

CEACAM8 is a cell adhesion molecule and a member of the immunoglobulin superfamily. It is expressed on the surface of granulocytes and plays a role in inflammation and immune response. It is also involved in the process of cell adhesion and in the activation of granulocytes.

Clinical significance[edit]

Alterations in the expression of CEACAM8 have been associated with various diseases, including cancer, inflammatory diseases, and infectious diseases. It has been suggested as a potential biomarker for these conditions.

Structure[edit]

The CEACAM8 protein is a type I transmembrane protein that consists of an extracellular region, a single transmembrane region, and a short cytoplasmic tail. The extracellular region contains three immunoglobulin-like domains.

Interactions[edit]

CEACAM8 has been shown to interact with other members of the CEA family, including CEACAM1, CEACAM3, and CEACAM6.

References[edit]

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