CUMYL-CB-MEGACLONE

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CUMYL-CB-MEGACLONE is a synthetic cannabinoid that has been identified in various designer drug products. It is a potent agonist of the cannabinoid receptors and is structurally related to other synthetic cannabinoids such as CUMYL-PEGACLONE and CUMYL-5F-PINACA.

Chemical Structure

CUMYL-CB-MEGACLONE belongs to the class of indazole-based synthetic cannabinoids. Its chemical structure includes a cumyl group attached to an indazole core, which is further connected to a cyclobutylmethyl group. The full chemical name is 1-(cyclobutylmethyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide.

Pharmacology

As a synthetic cannabinoid, CUMYL-CB-MEGACLONE acts as a potent agonist at the CB1 and CB2 cannabinoid receptors. These receptors are part of the endocannabinoid system, which plays a role in regulating various physiological processes including pain sensation, mood, and appetite.

Legal Status

The legal status of CUMYL-CB-MEGACLONE varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. It is often included in legislation targeting synthetic cannabinoids and other designer drugs.

Health Effects and Risks

The health effects of CUMYL-CB-MEGACLONE are not well-documented, but it is likely to share similar risks with other synthetic cannabinoids. These can include tachycardia, hypertension, nausea, vomiting, anxiety, and psychosis. There have been reports of severe adverse effects and fatalities associated with the use of synthetic cannabinoids.

Detection in Biological Samples

CUMYL-CB-MEGACLONE can be detected in biological samples using advanced analytical techniques such as liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS). These methods are commonly used in forensic and clinical toxicology to identify and quantify synthetic cannabinoids in blood, urine, and other tissues.

See Also

• Synthetic cannabinoids
• Cannabinoid receptor
• Designer drugs
• CUMYL-PEGACLONE
• CUMYL-5F-PINACA