CYP4Z1
CYP4Z1 is a gene that encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1. This family is known to metabolize fatty acids and is thought to play a role in the development of cancer.
Function[edit | edit source]
The CYP4Z1 gene encodes a member of the cytochrome P450 superfamily of enzymes. These enzymes are involved in the metabolism of a wide variety of substrates, including xenobiotics, fatty acids, and steroids. The specific function of CYP4Z1 is not well understood, but it is thought to play a role in the metabolism of fatty acids and the development of cancer.
Structure[edit | edit source]
The CYP4Z1 gene is located on the long (q) arm of chromosome 1 at position 36. The gene spans approximately 50 kilobases and consists of 13 exons. The encoded protein is 525 amino acids in length.
Clinical significance[edit | edit source]
CYP4Z1 has been implicated in the development of various types of cancer, including breast cancer and prostate cancer. Overexpression of CYP4Z1 has been observed in tumor tissues, suggesting a potential role in tumor progression.
See also[edit | edit source]
References[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD