Cannabidiolic acid

Cannabidiolic acid

Cannabidiolic acid (CBDA) is a cannabinoid found in the raw form of cannabis, specifically in the Cannabis sativa plant. It is a precursor to the more widely known cannabinoid, cannabidiol (CBD), and is produced through the process of decarboxylation.

Chemistry

CBDA is a carboxylic acid that consists of a phenol group and a pentyl chain. The carboxylic acid group is responsible for the 'A' in CBDA, standing for acid. When heated, this carboxylic acid group is removed in a process known as decarboxylation, converting CBDA into CBD.

Biosynthesis

CBDA is synthesized in the cannabis plant through the action of the enzyme CBDA synthase. This enzyme converts its precursor, cannabigerolic acid (CBGA), into CBDA.

Pharmacology

CBDA has been found to have several potential therapeutic effects. It has been shown to possess anti-inflammatory properties, and may also have anti-nausea effects. However, research into the pharmacology of CBDA is still in its early stages, and more studies are needed to fully understand its potential therapeutic uses.

Legal status

The legal status of CBDA varies by country and is often tied to the legal status of cannabis and CBD. In many jurisdictions, CBDA is considered a controlled substance under drug legislation.

See also

• Cannabinoid
• Cannabidiol
• Cannabis sativa
• Decarboxylation