Cellular blue nevus
Cellular blue nevus - a blue nevus characterized by a multinodular cellular infiltrate with a dumb bell architecture occupying the reticular dermis. The cellular infiltrate often extends into the subcutaneous tissue. The cellular infiltrate is composed of spindle shaped melanocytes with pale cytoplasm alternating with bundles of pigmented spindle shaped melanocytes. In occasional cases an increased mitotic activity, focal necrosis, and nuclear pleomorphism may be seen. Such cases with atypical features may have an uncertain malignant potential.
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Contributors: Prab R. Tumpati, MD
