Cepharanthine

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PubChem 10206
DrugBank
ChemSpider 9791
KEGG


Cepharanthine is an antiinflammatory and antineoplastic compound isolated from Stephania.[1] Due to these modalities, it has been shown effective against HTLV in lab research. [2] Additionally, it has successfully been used to treat a diverse range of medical conditions, including radiation-induced leukopenia, idiopathic thrombocytopenic purpura, alopecia areata, alopecia pityrodes, venomous snakebites, xerostomia, sarcoidosis, refractory anemia and various cancer-related conditions. No safety issues have been observed with CEP, and side effects are very rarely reported. [3]

References[edit | edit source]

  1. , Cepharanthine, an Alkaloid from Stephania cepharantha Hayata, Inhibits the Inflammatory Response in the RAW264.7 Cell and Mouse Models, Inflammation, 2013, Vol. 37(Issue: 1), pp. 235–46, DOI: 10.1007/s10753-013-9734-8, PMID: 24045962,
  2. , Synergistic inhibition of HTLV-1-infected cell proliferation by combination of cepharanthine and a tetramethylnaphthalene derivative, Anticancer Res., 2012, Vol. 32 pp. 2639–45, PMID: 22753721,
  3. , Therapeutic potential of the biscoclaurine alkaloid, cepharanthine, for a range of clinical conditions, Pharmacol Rep, Vol. 63 pp. 337-47, PMID: 21602589,



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