Charles Janeway

Charles Alderson Janeway Jr.

Birth date	February 5, 1943
Birth place	Boston, Massachusetts, USA
Died	April 12, 2003
Place of death	New Haven, Connecticut, USA
Nationality	American
Known for	Innate immune system

Charles Alderson Janeway Jr. (February 5, 1943 – April 12, 2003) was a prominent American immunologist who made significant contributions to the understanding of the innate immune system.

Early Life and Education

Charles Janeway was born in Boston, Massachusetts, into a family with a strong medical background. He attended Harvard Medical School, where he developed an interest in immunology.

Career

Janeway spent much of his career at Yale University, where he was a professor of immunobiology. His research focused on the mechanisms of the innate immune system and its role in the activation of the adaptive immune system.

Contributions to Immunology

Janeway is best known for his work on the innate immune system. He proposed that the innate immune system uses pattern recognition receptors to detect pathogens and initiate an immune response. This concept was foundational in the field of immunology and has influenced subsequent research on toll-like receptors.

Awards and Honors

Throughout his career, Janeway received numerous awards, including the American Association of Immunologists Lifetime Achievement Award. His work has had a lasting impact on the field of immunology.

Personal Life

Janeway was married and had two children. He passed away in New Haven, Connecticut, in 2003.

Legacy

Janeway's contributions to immunology are commemorated in the textbook "Janeway's Immunobiology", which is widely used in the field.

See Also

• Innate immune system
• Adaptive immune system
• Pattern recognition receptor
• Toll-like receptor

References

Kenneth,

 Janeway's Immunobiology, 
  
 Garland Science, 
 2012, 
  
  
 ISBN 978-0815345305,

Medzhitov, Ruslan,

 Charles Janeway and the innate immune system, 
 Nature Reviews Immunology, 
 2003, 
 Vol. 3(Issue: 11), 
 pp. 841-846, 
 DOI: 10.1038/nri1223,

External Links

• American Association of Immunologists - Charles A. Janeway