Chiasma

From WikiMD's Wellness Encyclopedia

Chiasma[edit | edit source]

A chiasma (plural: chiasmata) is a point at which paired chromosomes remain in contact during the first metaphase of meiosis, and at which crossing over and exchange of genetic material occur between the strands. This process is crucial for genetic diversity.

Structure and Formation[edit | edit source]

Chiasmata are formed during the prophase I stage of meiosis, specifically during the pachytene substage. During this time, homologous chromosomes pair up in a process known as synapsis, facilitated by the synaptonemal complex.

Synapsis[edit | edit source]

Synapsis is the pairing of two homologous chromosomes that occurs during meiosis. It allows for the exchange of genetic material between the chromosomes, a process known as genetic recombination.

Crossing Over[edit | edit source]

Crossing over is the process where homologous chromosomes exchange segments of genetic material. This occurs at the chiasmata and results in the recombination of genetic material, which increases genetic variation in the offspring.

Function[edit | edit source]

The primary function of chiasmata is to ensure the proper segregation of homologous chromosomes during meiosis. By holding the homologous chromosomes together, chiasmata help align them on the metaphase plate, ensuring that each daughter cell receives one chromosome from each homologous pair.

Importance in Genetic Diversity[edit | edit source]

Chiasmata and the associated process of crossing over are essential for genetic diversity. By exchanging genetic material between homologous chromosomes, new combinations of alleles are created, which can be passed on to offspring. This genetic variation is a key factor in evolution and adaptation.

Historical Context[edit | edit source]

The concept of chiasmata was first described by Franz Schrader and Barbara McClintock in the early 20th century. Their work laid the foundation for our understanding of genetic recombination and chromosome behavior during meiosis.

Related Concepts[edit | edit source]

References[edit | edit source]


External Links[edit | edit source]

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Contributors: Prab R. Tumpati, MD