Childhood absence epilepsy

Childhood Absence Epilepsy (CAE) is a form of epilepsy that is characterized by frequent, brief absence seizures. These seizures involve short periods, typically lasting less than 20 seconds, during which the child appears to be staring blankly or "zoning out." CAE typically manifests in children between the ages of 4 and 8 years and is one of the most common types of pediatric epilepsy. The condition is diagnosed through a combination of clinical history, characteristic findings on electroencephalogram (EEG), and the response to treatment. This article provides an overview of the symptoms, diagnosis, treatment, and prognosis of Childhood Absence Epilepsy.

Symptoms

The hallmark of CAE is the absence seizure, which often goes unnoticed due to its subtle nature. During a seizure, the child may stop their activity, stare blankly, and be unresponsive. These episodes can occur many times a day and interfere with learning and daily activities. Some children may also exhibit slight twitching movements or automatisms, such as lip-smacking or blinking. Unlike other forms of epilepsy, convulsive seizures are rare in CAE.

Diagnosis

Diagnosis of CAE is primarily based on the clinical history and characteristic EEG findings. The EEG typically shows a pattern known as "3 Hz spike-and-wave" discharges during these absence episodes. Video-EEG monitoring may be used to capture and confirm the diagnosis by recording the seizures and their corresponding EEG changes. Neuroimaging, such as MRI, is usually normal in CAE but may be performed to rule out other causes.

Treatment

The treatment of CAE focuses on controlling the absence seizures through medication. The first-line treatment is usually ethosuximide or valproic acid, which have been shown to be effective in controlling seizures in many children. Lamotrigine is another option, especially if the child has other types of seizures in addition to absence seizures. The choice of medication depends on the individual child's response and side effects. In some cases, children may outgrow CAE during adolescence, and medication can be gradually discontinued under careful medical supervision.

Prognosis

The prognosis for children with CAE is generally good, with many achieving seizure control with medication. However, some children may have learning difficulties or behavioral problems that require additional support. Regular follow-up with a neurologist is important to monitor seizure control, adjust medications as needed, and address any associated cognitive or behavioral issues.

See Also

• Epilepsy
• Seizure
• Electroencephalogram
• Pediatric epilepsy

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