Chlorphentermine hydrochloride

Chlorphentermine hydrochloride is a pharmacological agent, specifically a serotonin-releasing agent, which was used as an anorectic or weight loss medication. It is a member of the amphetamine family, and was developed in the 1960s as a medication to reduce appetite and assist in weight loss. However, due to its potential for abuse and addiction, it has been largely discontinued.

Pharmacology

Chlorphentermine hydrochloride acts primarily as a serotonin releasing agent. It stimulates the release of serotonin in the brain, which in turn suppresses appetite. This makes the individual feel full and reduces the desire to eat, thereby aiding in weight loss.

History

Chlorphentermine hydrochloride was developed in the 1960s as a medication to assist in weight loss. It was marketed under various brand names, including Apsedon, Desopimon, and Lucofen. However, due to concerns about its potential for abuse and addiction, as well as its side effects, it has been largely discontinued.

Side Effects

The side effects of chlorphentermine hydrochloride include insomnia, dry mouth, nausea, constipation, and nervousness. In addition, it can cause more serious side effects such as pulmonary hypertension and cardiovascular disease.

Regulation

Due to its potential for abuse and addiction, chlorphentermine hydrochloride is regulated under the Controlled Substances Act in the United States. It is classified as a Schedule III controlled substance, which means it has a potential for abuse less than substances in Schedules I and II, but abuse may lead to moderate or low physical dependence or high psychological dependence.

See Also

• Amphetamine
• Anorectic
• Controlled Substances Act