Choroid plexus papilloma
Editor-In-Chief: Prab R Tumpati, MD
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Choroid plexus papilloma, also known as papilloma of the choroid plexus, is a rare benign neuroepithelial intraventricular WHO grade I lesion found in the choroid plexus.[1] It leads to increased cerebrospinal fluid production, thus causing increased intracranial pressure and hydrocephalus.[2]
Choroid plexus papilloma occurs in the lateral ventricles of children and in the fourth ventricle of adults. This is unlike most other pediatric tumors and adult tumors, in which the locations of the tumors is reversed. In children, brain tumors are usually found in the infratentorial region and in adults, brain tumors are usually found in the supratentorial space. The relationship is reversed for choroid plexus papillomas.
Signs and symptoms[edit | edit source]
Signs of the tumor resulting from increased intracranial pressure are present in 91% of patients, with vomiting, homonymous visual field defects and headache being the most common symptoms. Other symptoms are ear ringing and dizziness.
Pathophysiology[edit | edit source]
The tumor is neuroectodermal in origin and similar in structure to a normal choroid plexus. They may be created by epithelial cells of the choroid plexus.
Micrograph of a choroid plexus papilloma. H&E stain.
Plexuspapillom Detail
Plexuspapillom Overview
Treatment[edit | edit source]
Choroid plexus papillomas are benign tumors that are usually cured by surgery; malignant progression has been rarely reported.
Epidemiology[edit | edit source]
Internationally tumors of the choroid plexus are rare, accounting for 0.4-0.6% of all intracranial neoplasms. It most commonly affects young children under the age of 5 with a mean patient age of 5.2 years.
References[edit | edit source]
External links[edit | edit source]
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| External resources |
- Choroid Plexus Papilloma MRI, CT, and pathology images from MedPix
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Contributors: Prab R. Tumpati, MD
