Cimlanod

Cimlanod is an antibiotic medication used to treat various bacterial infections. It belongs to the class of antibiotics known as macrolides. Cimlanod is effective against a wide range of Gram-positive and some Gram-negative bacteria.

Medical uses

Cimlanod is primarily used to treat infections such as:

• Respiratory tract infections
• Skin infections
• Soft tissue infections
• Urinary tract infections

Mechanism of action

Cimlanod works by inhibiting bacterial protein synthesis. It binds to the 50S subunit of the bacterial ribosome, thereby preventing the translocation of peptides. This action effectively halts bacterial growth and replication.

Pharmacokinetics

Cimlanod can be administered both orally and intravenously. It has a high bioavailability when taken orally and is widely distributed throughout the body. The drug is metabolized in the liver and excreted primarily through the kidneys.

Side effects

Common side effects of Cimlanod include:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain

Serious side effects may include:

• Allergic reactions
• Hepatotoxicity
• QT prolongation

Contraindications

Cimlanod should not be used in patients with known hypersensitivity to macrolide antibiotics. Caution is advised in patients with liver disease or those taking medications that can prolong the QT interval.

Interactions

Cimlanod may interact with other medications, including:

• Warfarin
• Theophylline
• Carbamazepine
• Digoxin

See also

• Antibiotic resistance
• List of antibiotics

References

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