Clorindione

Clorindione is an anticoagulant medication that is used to prevent and treat blood clots. It belongs to the class of drugs known as vitamin K antagonists. Clorindione works by reducing the body's ability to form blood clots. It is used in the treatment of conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and to prevent stroke in people with atrial fibrillation.

Mechanism of Action

Clorindione inhibits the synthesis of vitamin K-dependent clotting factors in the liver. These clotting factors are necessary for the blood to clot. By inhibiting their synthesis, Clorindione reduces the body's ability to form blood clots.

Uses

Clorindione is used to prevent and treat blood clots in conditions such as deep vein thrombosis and pulmonary embolism. It is also used to prevent stroke in people with atrial fibrillation.

Side Effects

Like all medications, Clorindione can cause side effects. The most common side effect is bleeding. Other side effects can include nausea, vomiting, abdominal pain, and diarrhea. In rare cases, Clorindione can cause serious side effects such as liver damage and bleeding in the brain.

Contraindications

Clorindione is contraindicated in people with certain conditions such as liver disease, kidney disease, and bleeding disorders. It is also contraindicated in pregnant women as it can cause birth defects.

Interactions

Clorindione can interact with many other medications, including other anticoagulants, antibiotics, and certain herbal supplements. It is important to tell your doctor about all the medications you are taking before starting Clorindione.

See Also

• Anticoagulant
• Vitamin K antagonist
• Deep vein thrombosis
• Pulmonary embolism
• Atrial fibrillation