Club cell
Club cell
A Club cell (also known as a Clara cell) is a type of cell in the bronchioles of the lungs. These cells are dome-shaped and have short microvilli, which are small projections on the surface of a cell that increase the cell's surface area. Club cells are found in the ciliated simple epithelium.
Function[edit | edit source]
Club cells serve several important functions in the lung. They secrete a variety of substances, including the Club cell secretory protein (CCSP), which helps to maintain the extracellular lining fluid of the airways. This protein has anti-inflammatory and immunomodulatory effects. Club cells also contribute to the defense of the lungs by detoxifying harmful substances inhaled into the lungs.
Clinical significance[edit | edit source]
Damage to Club cells can lead to a variety of lung diseases, including COPD and asthma. In addition, Club cell secretory protein has been used as a biomarker to detect lung damage, particularly in the context of occupational exposure to lung toxins.
See also[edit | edit source]
References[edit | edit source]
 | This anatomy article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
