Colin L. Masters

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Colin L. Masters is a renowned neurologist and biochemist who has made significant contributions to the field of neuroscience. He is best known for his research on Alzheimer's disease and other neurodegenerative diseases, particularly in the area of protein misfolding.

Early Life and Education[edit | edit source]

Masters was born in Australia and completed his undergraduate studies at the University of Sydney. He then went on to earn his medical degree from the same institution. Following his graduation, Masters moved to the United States to further his research at the National Institutes of Health (NIH).

Career[edit | edit source]

In 1981, Masters returned to Australia to join the University of Melbourne as a professor of pathology. He has since held numerous positions within the university, including the head of the Department of Pathology.

Masters' research primarily focuses on the molecular mechanisms underlying neurodegenerative diseases. He is particularly known for his work on Alzheimer's disease, where he has made significant contributions to understanding the role of protein misfolding in the disease's progression.

Research[edit | edit source]

Masters, along with his colleague Konrad Beyreuther, was the first to identify and sequence the amyloid beta protein, a key player in the development of Alzheimer's disease. This groundbreaking discovery has paved the way for further research into the causes and potential treatments for Alzheimer's.

Masters has also conducted extensive research on Creutzfeldt-Jakob disease (CJD), a rare and fatal brain disorder. His work in this area has led to a better understanding of the disease's pathology and potential treatment strategies.

Awards and Recognition[edit | edit source]

Over the course of his career, Masters has received numerous awards and recognitions for his contributions to neuroscience. These include the Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, and the Prince Mahidol Award in the field of medicine.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD