Confluent and Reticulated Papillomatosis
Confluent and Reticulated Papillomatosis
Confluent and Reticulated Papillomatosis (CRP) is a rare dermatological condition characterized by the presence of hyperpigmented, scaly papules that coalesce into reticulated plaques. These lesions typically appear on the trunk and neck, and the condition is more prevalent in young adults.
Etiology[edit | edit source]
The exact cause of CRP is not well understood. However, it is believed to be associated with abnormal keratinization and may have a genetic component. Some studies suggest a possible link to Malassezia yeast, although this is not definitively proven.
Clinical Presentation[edit | edit source]
Patients with CRP present with small, brownish papules that merge into larger, reticulated plaques. These lesions are often asymptomatic but can sometimes cause mild itching. The condition predominantly affects the trunk, particularly the upper back and chest, and can extend to the neck and axillae.
Diagnosis[edit | edit source]
Diagnosis of CRP is primarily clinical, based on the characteristic appearance of the lesions. A skin biopsy may be performed to rule out other conditions such as tinea versicolor, acanthosis nigricans, or seborrheic keratosis. Histopathological examination typically shows papillomatosis and hyperkeratosis.
Differential Diagnosis[edit | edit source]
CRP should be differentiated from other dermatological conditions that present with similar features:
Treatment[edit | edit source]
Treatment options for CRP include:
- Topical retinoids: Such as tretinoin, which help in normalizing keratinization.
- Oral antibiotics: Minocycline has been shown to be effective in some cases, possibly due to its anti-inflammatory properties.
- Keratolytics: Such as salicylic acid, which help in exfoliating the skin.
Prognosis[edit | edit source]
The prognosis for CRP is generally good, with many patients responding well to treatment. However, recurrences are common, and long-term management may be necessary.
Also see[edit | edit source]
Dermatology and Rheumatologic diseases A - Z
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