Corynebacterium minutissimum

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Corynebacterium minutissimum is a species of Gram-positive bacteria that belongs to the genus Corynebacterium. It is known for causing the skin infection erythrasma, which is characterized by reddish-brown patches on the skin, typically in areas where skin touches skin, such as the armpits, groin, and between the toes.

Characteristics

Corynebacterium minutissimum is a non-spore-forming, non-motile, rod-shaped bacterium. It is part of the normal skin flora but can become pathogenic under certain conditions. The bacterium is known for producing a characteristic coral-red fluorescence under Wood's lamp due to the production of porphyrins.

Pathogenesis

The primary infection caused by Corynebacterium minutissimum is erythrasma. This condition is more common in warm, humid climates and is often seen in individuals with diabetes mellitus or obesity. The infection is superficial and affects the stratum corneum of the skin.

Diagnosis

Diagnosis of erythrasma is typically made based on clinical appearance and confirmed by the characteristic coral-red fluorescence under a Wood's lamp. A skin biopsy and Gram stain can also be used to identify the presence of Corynebacterium minutissimum.

Treatment

Treatment for erythrasma usually involves topical or oral antibiotics. Commonly used topical treatments include clindamycin and erythromycin. Oral antibiotics such as tetracycline or clarithromycin may be prescribed for more extensive infections.

Prevention

Preventive measures include maintaining good personal hygiene, keeping skin dry, and using antibacterial soaps. Wearing loose-fitting clothing and avoiding excessive sweating can also help prevent the occurrence of erythrasma.

See also

• Corynebacterium
• Erythrasma
• Gram-positive bacteria
• Wood's lamp