Cotazym
Cotazym is a pancreatic enzyme supplement used to aid digestion in individuals who have insufficient pancreatic enzymes, a condition known as exocrine pancreatic insufficiency (EPI). This condition can be caused by various diseases, including cystic fibrosis, chronic pancreatitis, and pancreatic cancer.
Composition[edit | edit source]
Cotazym contains a mixture of three key enzymes:
- Lipase: Breaks down fats into fatty acids and glycerol.
- Protease: Breaks down proteins into peptides and amino acids.
- Amylase: Breaks down carbohydrates into simple sugars.
These enzymes are derived from porcine (pig) pancreas and are formulated to withstand the acidic environment of the stomach, ensuring they reach the small intestine where they are needed.
Indications[edit | edit source]
Cotazym is primarily indicated for the treatment of exocrine pancreatic insufficiency. It helps improve nutrient absorption and reduces symptoms such as steatorrhea (fatty stools), weight loss, and malnutrition.
Dosage and Administration[edit | edit source]
The dosage of Cotazym is individualized based on the severity of enzyme insufficiency and the fat content of meals. It is typically taken with meals and snacks to ensure enzymes are available when food is present in the digestive tract.
Side Effects[edit | edit source]
Common side effects of Cotazym may include:
Severe side effects are rare but can include allergic reactions and fibrosing colonopathy, particularly at high doses.
Related Conditions[edit | edit source]
See Also[edit | edit source]
- Pancreatic enzyme replacement therapy
- Lipase
- Protease
- Amylase
- Cystic fibrosis
- Chronic pancreatitis
- Pancreatic cancer
References[edit | edit source]
External Links[edit | edit source]
-
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Contributors: Prab R. Tumpati, MD