CureVac COVID-19 vaccine

From WikiMD's Food, Medicine & Wellness Encyclopedia

CureVac COVID-19 vaccine is a mRNA vaccine developed by CureVac, a German biopharmaceutical company, to combat the COVID-19 pandemic. The vaccine, also known as CVnCoV, is currently in the late-stage clinical trials.

Development[edit | edit source]

The development of the CureVac COVID-19 vaccine began in early 2020, following the outbreak of the COVID-19 pandemic. The vaccine uses messenger RNA (mRNA) technology, similar to the Pfizer-BioNTech COVID-19 vaccine and the Moderna COVID-19 vaccine. The mRNA in the vaccine provides instructions to cells in the body to produce a harmless piece of the SARS-CoV-2 virus, triggering an immune response.

Clinical Trials[edit | edit source]

The CureVac COVID-19 vaccine has undergone a series of clinical trials to test its safety and efficacy. The Phase 1 trial began in June 2020, with the Phase 2a trial starting in September 2020. The Phase 2b/3 trial, which involves around 36,500 participants, commenced in December 2020.

Efficacy[edit | edit source]

The efficacy of the CureVac COVID-19 vaccine is still under investigation. Preliminary results from the Phase 1/2a trials have shown promising results, with participants developing a strong immune response to the virus. The results of the Phase 2b/3 trial are expected to provide more definitive data on the vaccine's efficacy.

Side Effects[edit | edit source]

As with all vaccines, the CureVac COVID-19 vaccine may cause side effects. Common side effects reported in the clinical trials include pain at the injection site, fatigue, headache, muscle pain, and chills. Severe side effects are rare but can occur.

Distribution[edit | edit source]

The distribution of the CureVac COVID-19 vaccine is subject to the completion of clinical trials and approval by regulatory authorities such as the European Medicines Agency (EMA) and the Food and Drug Administration (FDA).

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD