Curschmann's spirals

Curschmann's spirals are a clinical finding often seen in the sputum of patients with asthma. They are named after the German physician Heinrich Curschmann, who first described them in 1897. Curschmann's spirals are formed from shed epithelium, and are a sign of severe inflammation and hypersecretion.

Overview

Curschmann's spirals are spiral-shaped mucus plugs from subepithelial mucous gland ducts or bronchioles. They may occur in several different lung diseases, including chronic bronchitis, asthma, and bronchiectasis. They are associated with excessive mucus production and inflammation.

Clinical significance

The presence of Curschmann's spirals in the sputum of a patient can be a sign of a severe asthma attack. They are often accompanied by Charcot-Leyden crystals, which are formed from the breakdown of eosinophils and can also be a sign of airway inflammation.

Diagnosis

Curschmann's spirals are diagnosed through microscopic examination of the patient's sputum. They appear as clear, colorless, spiral-shaped plugs, and can be seen under low magnification.

Treatment

Treatment for conditions that cause Curschmann's spirals involves managing the underlying condition. This may include medications to reduce inflammation and mucus production, as well as lifestyle changes such as quitting smoking and avoiding triggers for asthma attacks.

See also

• Asthma
• Chronic bronchitis
• Bronchiectasis
• Charcot-Leyden crystals

• 
  Curschmann's spirals