Cytolysis

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Cytolysis
Blausen 0684 OsmoticFlow Hypotonic.png
Synonyms Osmotic lysis
Pronounce N/A
Specialty Cell biology, Pathology
Symptoms Cell swelling, Cell rupture
Complications Tissue damage, Inflammation
Onset Rapid
Duration Variable, depending on exposure to hypotonic environment
Types N/A
Causes Hypotonic solution exposure, Bacterial toxins
Risks Hypotonic environment, Immune response
Diagnosis Microscopy, Cell culture
Differential diagnosis Apoptosis, Necrosis
Prevention Avoidance of hypotonic environments, Osmoregulation
Treatment Removal from hypotonic environment, supportive care
Medication N/A
Prognosis Depends on extent of cell damage
Frequency Common in laboratory settings, less common in vivo
Deaths N/A


Cytolysis is a process that occurs when a cell bursts due to an osmotic imbalance that has caused excess water to move into the cell. It is a form of cell death that results from a disease or an injury, such as hypotonic shock, and can also be induced by certain types of pathogens, like bacteria and viruses.

Causes of Cytolysis[edit | edit source]

Cytolysis can occur due to a variety of reasons. The most common cause is an osmotic imbalance, which can occur when a cell is in a hypotonic solution. This causes water to move into the cell, leading to swelling and eventually, bursting. Other causes include:

  • Pathogens: Certain types of bacteria and viruses can induce cytolysis in host cells.
  • Disease or Injury: Certain diseases or injuries can cause cells to burst.
  • Hypotonic Shock: This occurs when cells are suddenly exposed to a hypotonic solution, causing rapid water influx and cell bursting.

Consequences of Cytolysis[edit | edit source]

The bursting of a cell can have several consequences. It can lead to the release of cell contents into the surrounding environment, which can cause inflammation and damage to surrounding tissues. In addition, it can also lead to cell death, which can have significant impacts on the overall health of an organism.

Prevention and Treatment[edit | edit source]

Preventing cytolysis primarily involves maintaining a balanced osmotic environment for cells. This can be achieved through proper hydration and nutrition. In cases where cytolysis is caused by pathogens, treatment may involve the use of antibiotics or antiviral medications.

Cytolysis gallery[edit | edit source]

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD