DMPX
DMPX (3,7-dimethyl-1-propargylxanthine) is a xanthine derivative that acts as a potent and selective adenosine receptor antagonist. It is primarily used in scientific research to study the physiological and pharmacological roles of adenosine receptors.
Chemical Structure and Properties[edit | edit source]
DMPX is a methylated xanthine compound with the chemical formula C10H10N4O2. The structure of DMPX includes a xanthine core with methyl groups at the 3 and 7 positions and a propargyl group at the 1 position. This specific arrangement contributes to its high affinity and selectivity for adenosine receptors.
Mechanism of Action[edit | edit source]
DMPX functions by competitively inhibiting the binding of adenosine to its receptors. Adenosine is a neurotransmitter that plays a crucial role in various physiological processes, including sleep, cardiovascular function, and immune response. By blocking adenosine receptors, DMPX can modulate these processes, making it a valuable tool in pharmacological research.
Applications in Research[edit | edit source]
DMPX is widely used in neuroscience and pharmacology to investigate the role of adenosine receptors in different biological systems. It helps in understanding the effects of adenosine on central nervous system activities, such as sleep regulation, pain perception, and neuroprotection. Additionally, DMPX is used in cardiovascular research to study the impact of adenosine on heart rate and blood pressure.
Pharmacokinetics[edit | edit source]
The pharmacokinetics of DMPX, including its absorption, distribution, metabolism, and excretion, are critical for its effectiveness as a research tool. DMPX is known for its rapid absorption and ability to cross the blood-brain barrier, making it effective in central nervous system studies.
Safety and Handling[edit | edit source]
As with many research chemicals, proper safety protocols should be followed when handling DMPX. It should be used in a controlled laboratory environment, and appropriate personal protective equipment (PPE) should be worn to avoid exposure.
Related Compounds[edit | edit source]
DMPX is part of a broader class of xanthine derivatives, which include well-known compounds such as caffeine and theophylline. These compounds share a similar core structure but differ in their specific functional groups, leading to variations in their pharmacological effects.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
 | This medical article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
