DSC2

DSC2 is a gene that encodes the protein Desmocollin-2, a component of desmosomes. Desmosomes are cell structures that help connect adjacent cells. The DSC2 gene is located on the short (p) arm of chromosome 18 at position 11.1.

Function

The DSC2 gene provides instructions for making a protein called desmocollin-2. This protein is found in desmosomes, which are complexes of proteins that link adjacent cells together, particularly in the skin and heart. Desmocollin-2 helps cells stick to one another and provides strength and stability to tissues and organs.

Clinical significance

Mutations in the DSC2 gene have been associated with arrhythmogenic right ventricular cardiomyopathy (ARVC), a form of heart disease that often leads to life-threatening abnormal heart rhythms (arrhythmias).

See also

• Desmocollin
• Desmosome
• Arrhythmogenic right ventricular cardiomyopathy

External links

• DSC2 at NCBI
• DSC2 at Genetics Home Reference

DSC2 Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski

This article is a stub. You can help Wikipedia by expanding it.