Dapagliflozin/saxagliptin/metformin

From WikiMD's Wellness Encyclopedia

Dapagliflozin/Saxagliptin/Metformin is a combination medication used in the treatment of type 2 diabetes. It contains three active ingredients: dapagliflozin, saxagliptin, and metformin. This medication is used when diet and exercise alone does not control high blood sugar.

Composition[edit | edit source]

The medication is composed of three active ingredients:

  • Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It works by helping the kidneys get rid of glucose from your bloodstream.
  • Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the levels of insulin produced by your body and decreasing the amount of sugar made by your body.
  • Metformin is a biguanide. It works by decreasing the amount of sugar that your liver makes and that your stomach/intestines absorb.

Usage[edit | edit source]

This medication is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.

Side Effects[edit | edit source]

Common side effects of dapagliflozin/saxagliptin/metformin include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach upset
  • Gas
  • Headache
  • Weakness
  • Skin rash

Precautions[edit | edit source]

Before taking this medication, tell your doctor or pharmacist if you are allergic to dapagliflozin, saxagliptin, or metformin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD