Deep penetrating nevus

Deep Penetrating Nevus is a unique type of melanocytic nevus that is characterized by its distinct histological features. It was first described in the medical literature by Seab et al. in 1989.

Clinical Presentation

Deep Penetrating Nevus typically presents as a darkly pigmented lesion that is less than 6mm in diameter. It is most commonly found on the face, neck, and upper trunk of young adults. The lesion is usually asymptomatic, but it can sometimes cause mild discomfort or itching.

Histological Features

The histological features of Deep Penetrating Nevus are distinctive. The nevus cells are arranged in nests and cords that extend deeply into the dermis and sometimes into the subcutaneous fat. The cells are usually heavily pigmented and have a rounded or polygonal shape. They often show a pattern of maturation, with the cells becoming smaller and less pigmented as they descend into the dermis.

Differential Diagnosis

The differential diagnosis for Deep Penetrating Nevus includes other types of melanocytic nevi, such as Compound Nevus and Intradermal Nevus, as well as Melanoma. It is important to distinguish Deep Penetrating Nevus from these other conditions because the treatment and prognosis can be different.

Treatment

The standard treatment for Deep Penetrating Nevus is surgical excision. This is usually curative, and the risk of recurrence is low. However, it is important to monitor the patient closely for any signs of recurrence or malignant transformation.

Prognosis

The prognosis for Deep Penetrating Nevus is generally good. The risk of malignant transformation is low, but it is not zero. Therefore, it is important to monitor the patient closely for any signs of recurrence or malignant transformation.

See Also

• Melanocytic Nevus
• Compound Nevus
• Intradermal Nevus
• Melanoma

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