Dendrocyte expressed seven transmembrane protein

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Dendrocyte Expressed Seven Transmembrane Protein (also known as DESTM) is a protein that is encoded by the DES gene in humans. This protein is a member of the GPCR (G protein-coupled receptor) family, which is a large protein family of transmembrane receptors that sense molecules outside the cell and activate cellular responses.

Function[edit | edit source]

The DES gene provides instructions for making a protein called Dendrocyte Expressed Seven Transmembrane Protein. This protein is found in the dendrocytes, a type of cell that is involved in the immune response. The exact function of this protein is not well understood, but it is thought to play a role in the immune system.

Clinical significance[edit | edit source]

Mutations in the DES gene have been associated with a variety of medical conditions. For example, some studies have suggested that mutations in this gene may be associated with autoimmune diseases, although more research is needed to confirm these findings.

Research[edit | edit source]

Research into the function and role of the Dendrocyte Expressed Seven Transmembrane Protein is ongoing. Understanding more about this protein could lead to new treatments for a variety of diseases, including autoimmune diseases and other conditions that involve the immune system.

See also[edit | edit source]

References[edit | edit source]



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Contributors: Prab R. Tumpati, MD