Diabetic bulla

Diabetic bulla is a rare skin condition that is associated with diabetes mellitus. It is characterized by the sudden appearance of painless, large, tense blisters on the skin. These blisters are typically filled with clear, sterile fluid and can occur on normal or erythematous skin. The condition is also known as Bullosis Diabeticorum or Diabetic Bullous Disease.

Etiology

The exact cause of diabetic bulla is unknown. However, it is believed to be related to the damage caused to the blood vessels and nerves due to diabetes. The condition is more common in people with long-standing or poorly controlled diabetes.

Clinical Presentation

The bullae in diabetic bulla are usually large, ranging from 0.5 to several centimeters in diameter. They are typically located on the extremities, particularly on the backs of the hands, feet, toes, fingers, and sometimes on the legs or forearms. The bullae are usually painless and do not itch. They can last for several weeks and then heal spontaneously, often without scarring.

Diagnosis

Diagnosis of diabetic bulla is primarily based on the clinical presentation. The condition can be confirmed by a skin biopsy, which shows a subepidermal blister with a predominantly neutrophilic infiltrate.

Treatment

There is no specific treatment for diabetic bulla. The blisters usually heal spontaneously within a few weeks. However, it is important to control the underlying diabetes to prevent the occurrence of new blisters. In some cases, the blisters may need to be drained to relieve tension and prevent rupture.

Prognosis

The prognosis for diabetic bulla is generally good. The blisters usually heal without scarring. However, the condition can recur in some patients.

See Also

• Diabetes mellitus
• Skin conditions associated with diabetes

Diabetic bulla Resources
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