Dibenz(b,f)oxepin

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Chemical compound


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Dibenz(b,f)oxepin is a chemical compound that belongs to the class of tricyclic compounds. It is structurally related to doxepin, a well-known tricyclic antidepressant. Dibenz(b,f)oxepin is characterized by its three-ring structure, which includes a central oxepin ring.

Chemical Structure and Properties[edit | edit source]

Dibenz(b,f)oxepin has a unique chemical structure that consists of two benzene rings fused to an oxepin ring. This configuration is responsible for its chemical properties and potential biological activities. The molecular formula of dibenz(b,f)oxepin is C14H10O, and it has a molar mass of approximately 194.23 g/mol.

Pharmacology[edit | edit source]

While dibenz(b,f)oxepin itself is not widely used in clinical practice, its structural analogs, such as doxepin, are used as antidepressants and anxiolytics. These compounds work primarily by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine, thereby increasing their levels in the synaptic cleft and enhancing mood.

Synthesis[edit | edit source]

The synthesis of dibenz(b,f)oxepin involves the cyclization of appropriate precursors to form the tricyclic structure. This process typically requires specific conditions and catalysts to ensure the correct formation of the oxepin ring.

Applications[edit | edit source]

Research into dibenz(b,f)oxepin and its derivatives continues, as scientists explore their potential applications in pharmacology and medicinal chemistry. These compounds may serve as lead structures for the development of new therapeutic agents.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD