Diflucortolone
Diflucortolone is a corticosteroid used in dermatology to reduce inflammation and itching caused by certain skin conditions. It is a synthetic, fluorinated corticosteroid with anti-inflammatory, anti-pruritic, and vasoconstrictive properties.
Pharmacology[edit | edit source]
Diflucortolone's mechanism of action involves the induction of lipocortins, which are phospholipase A2 inhibitory proteins. These proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid.
Uses[edit | edit source]
Diflucortolone is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). It reduces the swelling, itching, and redness that can occur in these types of conditions.
Side Effects[edit | edit source]
Possible side effects of Diflucortolone include skin irritation, burning, redness, and dryness. More serious side effects may include stretch marks, skin thinning/discoloration, acne, excessive hair growth, "hair bumps" (folliculitis), and skin infections.
See Also[edit | edit source]
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