Dimethylaminopivalophenone

Dimethylaminopivalophenone (also known as DMP or Pivalophenone) is a chemical compound with the molecular formula C12H19NO. It is a derivative of phenone and is used in various synthetic processes in the chemical industry.

Chemical Structure

Dimethylaminopivalophenone is composed of a phenone core, which is a benzene ring bonded to a carbonyl group. Attached to this core is a pivaloyl group and a dimethylamino group. The pivaloyl group consists of a carbonyl group bonded to a tertiary carbon, which is a carbon atom bonded to three other carbon atoms. The dimethylamino group consists of a nitrogen atom bonded to two methyl groups.

Synthesis

The synthesis of Dimethylaminopivalophenone involves the reaction of pivaloyl chloride with dimethylamine in the presence of a base such as triethylamine. The resulting product is then reacted with phenylmagnesium bromide in a Grignard reaction to form the final product.

Applications

Dimethylaminopivalophenone is used as a building block in the synthesis of various other chemical compounds. It is particularly useful in the synthesis of pharmaceuticals and agrochemicals.

Safety

As with many chemical compounds, Dimethylaminopivalophenone should be handled with care. It can cause irritation to the skin and eyes, and may be harmful if swallowed or inhaled. Appropriate safety measures should be taken when handling this compound.

See Also

• Phenone
• Pivaloyl chloride
• Dimethylamine
• Triethylamine
• Phenylmagnesium bromide
• Grignard reaction