Dinitrofluorobenzene

Dinitrofluorobenzene (DNFB) is a chemical compound used primarily in scientific research. It is a yellow, crystalline solid that is soluble in organic solvents. DNFB is a potent skin sensitizer and is used in studies of allergic contact dermatitis.

Chemical Properties

Dinitrofluorobenzene has the chemical formula C6H3F(NO2)2. It is a derivative of benzene, with two nitro groups (-NO2) and one fluorine atom attached to the benzene ring. The presence of these substituents gives DNFB its unique chemical and physical properties.

Uses

In scientific research, DNFB is used as a skin sensitizer in studies of allergic contact dermatitis. When applied to the skin, it can induce an immune response, causing inflammation and itching. This makes it a useful tool for studying the immune system's response to allergens.

Health Effects

Exposure to DNFB can cause skin irritation and allergic reactions. In severe cases, it can cause a type of skin inflammation known as contact dermatitis. Long-term exposure can lead to sensitization, where the immune system becomes overly responsive to DNFB, leading to more severe allergic reactions.

Safety

Due to its potential health effects, DNFB should be handled with care. It should be stored in a cool, dry place, away from heat and open flames. Protective clothing, gloves, and eye protection should be worn when handling DNFB.

See Also

• Benzene
• Dermatitis
• Allergen