Diphenylpropylamine
Diphenylpropylamine is a class of opioid analgesics that are derived from phenylpropylamine. This class of drugs includes powerful pain relievers such as propoxyphene and dextropropoxyphene.
Chemistry[edit | edit source]
Diphenylpropylamine is a tertiary amine, meaning it has three groups attached to the nitrogen atom. The chemical formula for diphenylpropylamine is C23H27N. It is a white, crystalline substance that is soluble in water and alcohol.
Pharmacology[edit | edit source]
Diphenylpropylamine drugs work by binding to and activating the mu-opioid receptor in the brain. This receptor is responsible for the analgesic effects of opioids. When activated, it inhibits the release of pain signals, effectively reducing the perception of pain.
Medical Uses[edit | edit source]
Diphenylpropylamine drugs are primarily used for the treatment of moderate to severe pain. They are often prescribed when over-the-counter pain relievers, such as acetaminophen or ibuprofen, are not effective.
Side Effects[edit | edit source]
Like all opioids, diphenylpropylamine drugs have a risk of side effects. These can include drowsiness, nausea, constipation, and respiratory depression. There is also a risk of dependency and addiction with long-term use.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD