Disease cluster

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Disease cluster is a term used in epidemiology to refer to a geographic area or a period of time where a particular disease or health condition occurs more frequently than expected. The concept of disease clusters is important in public health and environmental health, as it can help identify potential environmental hazards or previously unknown diseases.

Definition[edit | edit source]

A disease cluster is defined as an unusual concentration of disease cases in a defined geographic area or time period. It is also defined as the occurrence of a greater-than-expected number of cases within a group of people, a geographic area, or a period of time.

Types of Disease Clusters[edit | edit source]

There are several types of disease clusters, including:

  • Geographic clusters: These are clusters where a high number of cases occur in a specific geographic area. This could be due to environmental factors in that area, such as pollution or a high presence of a certain type of insect or animal that carries the disease.
  • Temporal clusters: These are clusters where a high number of cases occur within a specific time period. This could be due to a seasonal outbreak of a disease, or a sudden increase in cases due to a new strain of a disease.
  • Population clusters: These are clusters where a high number of cases occur within a specific population group. This could be due to genetic factors, lifestyle factors, or exposure to a specific risk factor within that population group.

Investigation of Disease Clusters[edit | edit source]

Investigation of disease clusters involves several steps, including:

  • Initial assessment: This involves gathering preliminary information about the suspected cluster, including the number of cases, the geographic area, and the time period.
  • Case confirmation: This involves confirming the diagnosis of the disease in the reported cases.
  • Assessment of expected number of cases: This involves comparing the observed number of cases to the expected number of cases based on population data.
  • Epidemiological study: If the observed number of cases is significantly higher than the expected number, an epidemiological study may be conducted to identify potential causes of the cluster.

Examples of Disease Clusters[edit | edit source]

Some examples of disease clusters include:

  • The Love Canal incident in the 1970s, where a high number of birth defects and cancers were reported in a neighborhood built on a toxic waste dump.
  • The Lyme disease outbreak in Lyme, Connecticut in the 1970s, which led to the discovery of the disease.
  • The AIDS epidemic in the 1980s, which was initially identified as a cluster of cases among gay men in Los Angeles and New York.

See Also[edit | edit source]

Disease cluster Resources
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Contributors: Prab R. Tumpati, MD