Donnatal

Donnatal is a prescription medication used primarily for the treatment of irritable bowel syndrome (IBS) and acute enterocolitis. It is a combination drug that contains phenobarbital, hyoscyamine, atropine, and scopolamine. These components work together to relieve symptoms such as cramping, abdominal pain, and diarrhea.

Composition

Donnatal is composed of the following active ingredients:

• Phenobarbital: A barbiturate that acts as a sedative and anticonvulsant.
• Hyoscyamine: An anticholinergic that helps to reduce muscle spasms in the gastrointestinal tract.
• Atropine: Another anticholinergic that reduces bodily secretions and relaxes muscles.
• Scopolamine: An anticholinergic that prevents nausea and vomiting.

Mechanism of Action

The combination of these ingredients works by decreasing the motion of the stomach and intestines and by relaxing the muscles in the gastrointestinal tract. This helps to alleviate the symptoms associated with IBS and enterocolitis.

Indications

Donnatal is indicated for the treatment of:

• Irritable bowel syndrome (IBS)
• Acute enterocolitis

Side Effects

Common side effects of Donnatal may include:

• Drowsiness
• Dizziness
• Dry mouth
• Blurred vision
• Constipation

Serious side effects may include:

• Difficulty urinating
• Rapid heartbeat
• Severe allergic reactions

Contraindications

Donnatal should not be used in individuals with:

• Glaucoma
• Myasthenia gravis
• Obstructive uropathy
• Severe ulcerative colitis

Dosage and Administration

Donnatal is available in various forms, including tablets, extended-release tablets, and elixir. The dosage and administration depend on the specific condition being treated and the patient's response to the medication.

Related Pages

• Phenobarbital
• Hyoscyamine
• Atropine
• Scopolamine
• Irritable bowel syndrome
• Enterocolitis