Dorsal column nuclei

Dorsal column nuclei are a pair of nuclei in the dorsal columns of the medulla oblongata. They are also known as the gracile nucleus and cuneate nucleus. These nuclei are part of the somatosensory system and are involved in the sensation of fine touch and proprioception (body position).

Anatomy

The dorsal column nuclei are located in the medulla oblongata, the lower half of the brainstem. They consist of two pairs of nuclei: the gracile nucleus and the cuneate nucleus. The gracile nucleus is located medially and receives sensory input from the lower body and legs, while the cuneate nucleus is located laterally and receives sensory input from the upper body and arms.

Function

The dorsal column nuclei are part of the dorsal column-medial lemniscus pathway, a sensory pathway of the central nervous system. This pathway is responsible for transmitting information about fine touch, vibration, and proprioception from the body to the brain. The information is sent from the receptors in the skin and muscles to the dorsal column nuclei, where it is processed and sent to the thalamus and then to the cortex.

Clinical significance

Damage to the dorsal column nuclei can result in a loss of fine touch and proprioception. This can be caused by a variety of conditions, including stroke, multiple sclerosis, and neurodegenerative diseases. Treatment typically involves managing the underlying condition and may include physical therapy to help improve proprioception.

See also

• Medulla oblongata
• Somatosensory system
• Dorsal column-medial lemniscus pathway

References

Dorsal column nuclei Resources
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