Dorsolateral prefrontal cortex

From WikiMD's Wellness Encyclopedia

Dorsolateral Prefrontal Cortex

The Dorsolateral Prefrontal Cortex (DLPFC) is an area in the prefrontal cortex of the brain of humans and other primates. It is one of the most recently evolved parts of the brain. It has connections with the orbitofrontal cortex, parietal cortex, and the anterior cingulate cortex.

Etymology[edit | edit source]

The term "Dorsolateral Prefrontal Cortex" can be broken down into three parts: "Dorso-", "lateral", and "prefrontal cortex". "Dorso-" comes from the Latin word "dorsum" which means back. "Lateral" is derived from the Latin word "latus" which means side. "Prefrontal cortex" refers to the front part of the brain.

Function[edit | edit source]

The DLPFC is involved in executive functions such as working memory, cognitive flexibility, planning, inhibition, and abstract reasoning. It is also involved in the integration of sensory and memory information. The DLPFC is also known to play a role in attention and emotion regulation.

Clinical significance[edit | edit source]

Damage to the DLPFC can result in several cognitive deficits including difficulties with abstract thinking, problem solving, and planning. It is also associated with psychiatric disorders such as schizophrenia, depression, and ADHD.

Related terms[edit | edit source]

See also[edit | edit source]

References[edit | edit source]


Dorsolateral prefrontal cortex Resources
Wikipedia
WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD