Drug-induced keratoderma
Drug-induced keratoderma | |
---|---|
Synonyms | |
Pronounce | N/A |
Specialty | Dermatology |
Symptoms | Thickening of the skin on the palms and soles |
Complications | |
Onset | |
Duration | |
Types | N/A |
Causes | Drug reaction |
Risks | |
Diagnosis | Clinical diagnosis |
Differential diagnosis | Palmoplantar keratoderma, Psoriasis, Eczema |
Prevention | Avoidance of causative drugs |
Treatment | Discontinuation of the offending drug, topical treatments |
Medication | Keratolytics, Emollients |
Prognosis | Generally good with drug discontinuation |
Frequency | Rare |
Deaths | N/A |
Drug-induced keratoderma is a condition characterized by the thickening of the skin on the palms of the hands and the soles of the feet. This condition is caused by the use of certain medications.
Causes[edit | edit source]
Drug-induced keratoderma is caused by the use of certain medications. These medications include retinoids, cytotoxic drugs, and antiretroviral drugs. The exact mechanism by which these drugs cause keratoderma is not fully understood.
Symptoms[edit | edit source]
The main symptom of drug-induced keratoderma is the thickening of the skin on the palms of the hands and the soles of the feet. This thickening can be accompanied by other symptoms such as redness, itching, and pain.
Diagnosis[edit | edit source]
The diagnosis of drug-induced keratoderma is made based on the patient's medical history, physical examination, and the results of skin biopsy. The skin biopsy can show characteristic changes in the skin that are indicative of keratoderma.
Treatment[edit | edit source]
The treatment of drug-induced keratoderma involves discontinuing the offending medication and treating the symptoms. Topical treatments such as emollients and keratolytics can be used to soften the skin and reduce the thickness of the skin. In severe cases, systemic treatments such as retinoids may be used.
See also[edit | edit source]
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