Drug categories S

Drug Category Names, Results, and Descriptions

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• Sensory System Agents  (502) • Drugs that act on neuronal sensory receptors resulting in an increase, decrease, or modification of afferent nerve activity. (From Smith and Reynard, Textbook of Pharmacology, 1991, p367)

• Sequestering Agents  (96) • Compounds that bind to and reduce the biological availability of a chemical or pharmaceutical agent.

• Serine Proteinase Inhibitors  (63) • Exogenous or endogenous compounds which inhibit SERINE ENDOPEPTIDASES.

• Serine Proteinase Inhibitors, Endogenous  (0) see Serine Proteinase Inhibitors

• Serine Proteinase Inhibitors, Exogenous  (0) see Serine Proteinase Inhibitors

• Serotonin 5-HT1 Receptor Agonists  (13) • Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT1 RECEPTORS. Included under this heading are agonists for one or more of the specific 5-HT1 receptor subtypes.

• Serotonin 5-HT1 Receptor Antagonists  (5) • Drugs that bind to but do not activate SEROTONIN 5-HT1 RECEPTORS, thereby blocking the actions of SEROTONIN 5-HT1 RECEPTOR AGONISTS. Included under this heading are antagonists for one or more of the specific 5-HT1 receptor subtypes.

• Serotonin 5-HT1A Receptor Agonists  (0) see Serotonin 5-HT1 Receptor Agonists

• Serotonin 5-HT1A Receptor Antagonists  (0) see Serotonin 5-HT1 Receptor Antagonists

• Serotonin 5-HT1B Receptor Agonists  (0) see Serotonin 5-HT1 Receptor Agonists

• Serotonin 5-HT1B Receptor Antagonists  (0) see Serotonin 5-HT1 Receptor Antagonists

• Serotonin 5-HT1B-D Agonists  (0) see Serotonin 5-HT1 Receptor Agonists

• Serotonin 5-HT1B-D Antagonists  (0) see Serotonin 5-HT1 Receptor Antagonists

• Serotonin 5-HT1D Receptor Agonists  (0) see Serotonin 5-HT1 Receptor Agonists

• Serotonin 5-HT1D Receptor Antagonists  (0) see Serotonin 5-HT1 Receptor Antagonists

• Serotonin 5-HT2 Receptor Agonists  (4)

• Serotonin 5-HT2 Receptor Antagonists  (5) • Drugs that bind to but do not activate SEROTONIN 5-HT2 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN 5-HT2 RECEPTOR AGONISTS. Included under this heading are antagonists for one or more specific 5-HT2 receptor subtypes.

• Serotonin 5-HT2A Receptor Antagonists  (0) see Serotonin 5-HT2 Receptor Antagonists

• Serotonin 5-HT2B Receptor Antagonists  (0) see Serotonin 5-HT2 Receptor Antagonists

• Serotonin 5-HT2C Receptor Antagonists  (0) see Serotonin 5-HT2 Receptor Antagonists

• Serotonin 5-HT3 Receptor Antagonists  (3)

• Serotonin 5-HT4 Receptor Agonists  (3)

• Serotonin Agents  (175) • Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons.

• Serotonin Agonists  (12)

• Serotonin and Noradrenaline Reuptake Inhibitors  (3) • Drugs that selectively block or suppress the plasma membrane transport of SEROTONIN and NORADRENALINE into axon terminals and are used as ANTIDEPRESSIVE AGENTS.

• Serotonin Antagonists  (86) • Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS.

• Serotonin Effect  (0) see Serotonin Agents

• Serotonin Receptor Agonists  (69) • Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.

• Serotonin Uptake Inhibitors  (22) • Compounds that specifically inhibit the reuptake of serotonin in the brain.

• Sex Hormone Synthesis Inhibitors  (0) see Steroid Synthesis Inhibitors

• Siderophores  (10) • Low-molecular-weight compounds produced by microorganisms that aid in the transport and sequestration of ferric iron. (The Encyclopedia of Molecular Biology, 1994)

• Skeletal Muscle Relaxants  (0) see Neuromuscular Agents

• Sleep Aids, Pharmaceutical  (5) • Drugs used to induce SLEEP, prevent SLEEPLESSNESS, or treat SLEEP INITIATION AND MAINTENANCE DISORDERS.

• Small GTPase Activators  (0) see GTP Phosphohydrolase Activators

• Sodium Channel Agonists  (2)

• Sodium Channel Blockers  (28) • A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.

• Sodium Chloride Symporter Inhibitors  (15) • Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA.

• Sodium Ionophores  (1) • Chemical agents that increase the permeability of CELL MEMBRANES to SODIUM ions.

• Sodium Potassium Chloride Symporter Inhibitors  (5) • Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.

• Soil Pollutants  (4) • Substances which pollute the soil. Use for soil pollutants in general or for which there is no specific heading.

• Solvents  (21) • Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)

• Spermatocidal Agents  (5) • Chemical substances that are destructive to spermatozoa used as topically administered vaginal contraceptives.

• Stabilizing Agents  (0) see Excipients

• Stains  (0) see Coloring Agents

• Steroid Synthesis Inhibitors  (43) • Compounds that bind to and inhibit enzymes involved in the synthesis of STEROIDS.

• Stromelysin Inhibitors  (0) see Matrix Metalloproteinase Inhibitors

• Sugar Substitutes  (0) see Sweetening Agents

• Sulfhydryl Compound Antagonists  (0) see Sulfhydryl Reagents

• Sulfhydryl Compounds Inhibitors  (0) see Sulfhydryl Reagents

• Sulfhydryl Reagents  (10) • Chemical agents that react with SH groups. This is a chemically diverse group that is used for a variety of purposes. Among these are enzyme inhibition, enzyme reactivation or protection, and labelling.

• Sunscreening Agents  (14) • Chemical or physical agents that protect the skin from sunburn and erythema by absorbing or blocking ultraviolet radiation.

• Surface-Active Agents  (69) • Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.

• Surfactants  (0) see Surface-Active Agents

• Surgical Fixation Devices  (9)

• Suspending Agents  (0) see Excipients

• Sustained-Release Preparations  (0) see Delayed-Action Preparations

• Sweetening Agents  (22) • Substances that sweeten food, beverages, medications, etc., such as sugar, saccharine or other low-calorie synthetic products. (From Random House Unabridged Dictionary, 2d ed)

• Sympathetic Transmitter Releasers  (0) see Adrenergic Agents

• Sympatholytic Effect  (0) see Sympatholytics

• Sympatholytics  (24) • Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here.

• Sympathomimetic Effect  (0) see Sympathomimetics

• Sympathomimetics  (63) • Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.

Drug Category Names, Results, and Descriptions

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