ERVWE1
ERVWE1 is a human gene that encodes the glycoprotein (g) syncytin-1, which is involved in the formation of the syncytiotrophoblast, a tissue essential for placental development and function. The gene is part of the endogenous retrovirus group W envelope (ERVWE1) family.
Function[edit | edit source]
The ERVWE1 gene provides instructions for making a protein called syncytin-1. This protein is critical for the development and function of the placenta, which attaches the developing fetus to the uterine wall to allow nutrient uptake, waste elimination, and gas exchange via the mother's blood supply.
Syncytin-1 is involved in the formation of the syncytiotrophoblast, a specialized tissue that lines the placenta and interfaces with the mother's blood supply. The syncytiotrophoblast is formed by the fusion of cells called cytotrophoblasts, a process that is facilitated by syncytin-1.
Clinical significance[edit | edit source]
Mutations in the ERVWE1 gene can lead to placental dysfunction, which can result in complications during pregnancy, including preeclampsia, intrauterine growth restriction, and preterm birth.
See also[edit | edit source]
References[edit | edit source]
| ERVWE1 Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
