Eccrine poroma

Eccrine Poroma
Synonyms
Pronounce	N/A
Specialty	N/A
Symptoms	Solitary, slow-growing, flesh-colored nodule
Complications	Rarely malignant transformation
Onset	Middle-aged adults
Duration	Chronic
Types	N/A
Causes	Proliferation of eccrine sweat gland cells
Risks
Diagnosis	Clinical examination, dermoscopy, histopathology
Differential diagnosis	N/A
Prevention	N/A
Treatment	Surgical excision
Medication	N/A
Prognosis	Excellent with treatment
Frequency	Rare
Deaths	N/A

Eccrine poroma is a benign skin tumor that arises from the eccrine sweat glands. It typically presents as a solitary, slow-growing, flesh-colored nodule, often located on the sole of the foot or other areas of the body where eccrine glands are abundant.

Pathophysiology

Eccrine poromas originate from the intraepidermal portion of the eccrine sweat duct. The tumor is composed of poroid cells, which are small, cuboidal cells that resemble the cells of the eccrine sweat gland duct. These tumors are thought to arise due to a proliferation of these cells, although the exact mechanism is not fully understood.

Clinical Presentation

Eccrine poromas are most commonly found in middle-aged adults. They present as a solitary, well-circumscribed, dome-shaped nodule. The lesion is typically flesh-colored, pink, or red and may have a smooth or verrucous surface. While they can occur anywhere on the body, they are most frequently found on the palms and soles.

Diagnosis

The diagnosis of an eccrine poroma is primarily clinical, supported by dermoscopic examination and confirmed by histopathological analysis.

Dermoscopy

Dermoscopy of an eccrine poroma may reveal a vascular pattern with linear, branched, or glomerular vessels. The surface may show a pinkish hue with white streaks.

Histopathology

Histologically, eccrine poromas are characterized by nests of poroid cells within the epidermis and extending into the dermis. The cells are small, with round nuclei and scant cytoplasm. Ductal structures may be present, and the stroma is typically fibrous.

Differential Diagnosis

The differential diagnosis for eccrine poroma includes:

• Basal cell carcinoma
• Squamous cell carcinoma
• Seborrheic keratosis
• Pyogenic granuloma

Treatment

The treatment of choice for eccrine poroma is surgical excision. Complete excision is usually curative, and recurrence is rare. Other treatment modalities, such as cryotherapy or laser ablation, are less commonly used.

Prognosis

The prognosis for patients with eccrine poroma is excellent following surgical excision. Malignant transformation to eccrine porocarcinoma is rare but can occur, necessitating careful histological examination of excised lesions.

Epidemiology

Eccrine poromas are rare tumors, with no significant predilection for any particular ethnic group or gender. They are most commonly diagnosed in middle-aged adults.

See Also

• Eccrine sweat gland
• Porocarcinoma
• Skin neoplasm

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