Elongation
Elongation is a crucial phase in the process of protein synthesis and DNA replication. It involves the addition of amino acids to the growing polypeptide chain during protein synthesis and the addition of nucleotides to the DNA strand during DNA replication.
Protein Synthesis[edit | edit source]
During protein synthesis, elongation is the second of three stages. It follows the initiation stage and precedes the termination stage. In this phase, amino acids are added one by one to the growing polypeptide chain. The process is facilitated by ribosomes, which move along the mRNA molecule, reading its sequence and incorporating the appropriate amino acids.
DNA Replication[edit | edit source]
In DNA replication, elongation is the process where DNA polymerase adds nucleotides to the growing DNA strand. This process is highly regulated to ensure accuracy and prevent mutations. The DNA polymerase reads the original DNA strand and adds complementary nucleotides to the new strand.
Role in Cell Growth and Development[edit | edit source]
Elongation plays a vital role in cell growth and development. It is responsible for the production of proteins and the replication of DNA, which are essential for cell division and growth. Any errors in the elongation process can lead to mutations and potentially to diseases such as cancer.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD