Ensulizole

From WikiMD's Food, Medicine & Wellness Encyclopedia

Ensulizole

Ensulizole, also known as phenylbenzimidazole sulfonic acid, is a chemical compound commonly used in sunscreens and other personal care products. It is a broad-spectrum ultraviolet (UV) filter that primarily absorbs UVB radiation, protecting the skin from harmful effects of the sun.

Properties and Mechanism of Action[edit | edit source]

Ensulizole is a white crystalline powder that is soluble in water and organic solvents. It is stable under normal conditions and does not degrade easily when exposed to light or heat. This makes it an ideal ingredient for sunscreens, as it provides long-lasting protection against UV radiation.

The mechanism of action of ensulizole involves the absorption of UVB radiation. When applied to the skin, it forms a thin film that acts as a barrier, preventing UVB rays from penetrating the skin. This helps to prevent sunburn and reduces the risk of skin cancer caused by excessive sun exposure.

Safety and Regulatory Status[edit | edit source]

Ensulizole has been extensively tested for safety and is approved for use in sunscreens by regulatory authorities such as the U.S. Food and Drug Administration (FDA) and the European Union's Scientific Committee on Consumer Safety (SCCS). It has a long history of use in personal care products and has been found to be non-irritating and non-sensitizing to the skin.

However, like all chemical compounds, ensulizole should be used in accordance with the instructions provided by the manufacturer. It is important to apply sunscreen generously and reapply it regularly, especially after swimming or sweating, to maintain its effectiveness.

Environmental Impact[edit | edit source]

Ensulizole is considered to have a low environmental impact. It is not persistent in the environment and does not bioaccumulate in organisms. Studies have shown that it does not pose a significant risk to aquatic life when used as directed.

Alternatives and Complementary Ingredients[edit | edit source]

Ensulizole is often used in combination with other UV filters to provide broad-spectrum protection against both UVA and UVB radiation. Commonly used complementary ingredients include avobenzone, octocrylene, and titanium dioxide. These ingredients work together to enhance the overall sun protection factor (SPF) of the sunscreen product.

References[edit | edit source]

1. U.S. Food and Drug Administration. (2020). Sunscreen: How to Help Protect Your Skin from the Sun. Retrieved from [1]

2. European Commission. (2015). Scientific Committee on Consumer Safety. Opinion on Ensulizole. Retrieved from [2]

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD