Epineurium

Epineurium is the outermost layer of the Peripheral Nerve that provides mechanical strength and protection. It is composed of dense irregular Connective Tissue and contains blood vessels that supply the nerve.

Structure

The Epineurium is a layer of dense connective tissue that surrounds a peripheral nerve. It encloses the individual Fascicles, which are bundles of Axons, and the Perineurium, another protective layer. The Epineurium contains Blood Vessels and Lymphatic Vessels that supply the nerve.

Function

The primary function of the Epineurium is to protect the nerve from mechanical injury. It also provides a barrier against the spread of infections and tumors. The blood vessels within the Epineurium supply nutrients to the nerve and remove waste products.

Clinical Significance

Damage to the Epineurium can lead to Peripheral Neuropathy, a condition characterized by weakness, numbness, and pain from nerve damage, typically in the hands and feet. It can also be involved in the spread of Neoplastic Diseases.

See Also

• Peripheral Nerve
• Fascicles
• Axons
• Perineurium
• Connective Tissue
• Blood Vessels
• Lymphatic Vessels
• Peripheral Neuropathy
• Neoplastic Diseases

Epineurium Resources
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