Erythroleukemia

Erythroleukemia is a rare form of leukemia characterized by the abnormal proliferation of red blood cells in the bone marrow. It is also known as Di Guglielmo syndrome.

Overview

Erythroleukemia is a subtype of acute myeloid leukemia (AML), specifically categorized as M6 under the French-American-British classification. It is characterized by the presence of erythroblasts in the bone marrow, which are immature red blood cells. This condition is rare, accounting for less than 5% of all AML cases.

Symptoms

The symptoms of erythroleukemia are similar to other forms of leukemia and may include fatigue, weakness, shortness of breath, pale skin, fever, easy bruising or bleeding, and frequent infections.

Diagnosis

The diagnosis of erythroleukemia is based on the examination of the bone marrow. A bone marrow biopsy is performed to confirm the presence of abnormal erythroblasts. Other diagnostic tests may include blood tests, genetic testing, and imaging tests.

Treatment

The treatment for erythroleukemia typically involves chemotherapy to destroy the abnormal cells. In some cases, a stem cell transplant may be considered. The choice of treatment depends on the patient's overall health, age, and the specific characteristics of the leukemia.

Prognosis

The prognosis for erythroleukemia varies depending on several factors, including the patient's age, overall health, and response to treatment. In general, the prognosis is poor, with a median survival time of less than a year.

See also

• Leukemia
• Acute myeloid leukemia
• Bone marrow biopsy
• Chemotherapy
• Stem cell transplant

Erythroleukemia Resources
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