Erythroleukemia

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Erythroleukemia is a rare form of leukemia characterized by the abnormal proliferation of red blood cells in the bone marrow. It is also known as Di Guglielmo syndrome.

Overview[edit | edit source]

Erythroleukemia is a subtype of acute myeloid leukemia (AML), specifically categorized as M6 under the French-American-British classification. It is characterized by the presence of erythroblasts in the bone marrow, which are immature red blood cells. This condition is rare, accounting for less than 5% of all AML cases.

Symptoms[edit | edit source]

The symptoms of erythroleukemia are similar to other forms of leukemia and may include fatigue, weakness, shortness of breath, pale skin, fever, easy bruising or bleeding, and frequent infections.

Diagnosis[edit | edit source]

The diagnosis of erythroleukemia is based on the examination of the bone marrow. A bone marrow biopsy is performed to confirm the presence of abnormal erythroblasts. Other diagnostic tests may include blood tests, genetic testing, and imaging tests.

Treatment[edit | edit source]

The treatment for erythroleukemia typically involves chemotherapy to destroy the abnormal cells. In some cases, a stem cell transplant may be considered. The choice of treatment depends on the patient's overall health, age, and the specific characteristics of the leukemia.

Prognosis[edit | edit source]

The prognosis for erythroleukemia varies depending on several factors, including the patient's age, overall health, and response to treatment. In general, the prognosis is poor, with a median survival time of less than a year.

See also[edit | edit source]


Erythroleukemia Resources

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Contributors: Bonnu, Prab R. Tumpati, MD, Dr.T