Stem cell transplant
Stem cell transplant also known as Hematopoietic stem cell transplantation (HSCT) involves the intravenous (IV) infusion of autologous or allogeneic stem cells to reestablish hematopoietic function in patients whose bone marrow or immune system is damaged or defective. They can be harvested from the donor's bone marrow, peripheral blood, or umbilical cord blood shortly after delivery of neonates.
Types[edit | edit source]
There are two main types of HSCT, Autologous and Allogeneic stem cell transplant. Autologous HSCT requires the extraction of stem cells from the patient and their subsequent reinfusion after a conditioning regimen, while Allogeneic HSCT involves stem cells from a donor after a conditioning regimen.
Uses[edit | edit source]
Stem cell transplants are used to treat patients whose stem cells have been damaged by disease or the treatment thereof, particularly in cancers such as Leukemia, Lymphoma, and Multiple Myeloma. They can also be used for Aplastic Anemia, Immune Deficiencies, and some solid tumor cancers.
Procedure[edit | edit source]
The procedure for stem cell transplant varies depending on the type of transplant, the disease requiring transplant, and the patient's health status. Generally, it involves the administration of high-dose chemotherapy or radiation therapy, followed by the infusion of stem cells into the patient's bloodstream.
Risks and Complications[edit | edit source]
Stem cell transplant comes with several risks and complications, including Graft-versus-host disease (GVHD), Stem cell (graft) failure, Organ damage, Infections, Cataracts, Infertility, New cancers, and Death.
See Also[edit | edit source]
- Bone marrow transplant
- Cord blood bank
- Graft-versus-host disease
- Immunosuppressive drug
- Transplant rejection
Stem cell transplant Resources | |
---|---|
|
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD