Estradiol 3-propionate

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Estradiol 3-propionate is a synthetic, steroidal estrogen and an estrogen ester – specifically, the 3-propionate ester of estradiol – which is not marketed. It is a long-acting estrogen, and acts as a prodrug of estradiol in the body. Estradiol 3-propionate is used in scientific research to study the effects of estrogens.

Chemistry[edit | edit source]

Estradiol 3-propionate, also known as E2-3-P and 17β-estradiol 3-propionate, is a synthetic estrane steroid and a derivative of estradiol. It is an estrogen ester; specifically, it is the 3-propionate ester of estradiol. Other important estrogen esters include estradiol benzoate and estradiol valerate.

Pharmacology[edit | edit source]

As a prodrug of estradiol, estradiol 3-propionate has the same mechanism of action and effects as estradiol. It interacts with the estrogen receptor to produce its effects. The propionate ester is cleaved in the body, releasing estradiol.

Research[edit | edit source]

Estradiol 3-propionate has been used in scientific research to study the effects of estrogens. It has been used in studies on breast cancer, osteoporosis, and menopause.

See also[edit | edit source]


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