Estradiol valerate/cyproterone acetate

Estradiol valerate/cyproterone acetate is a combined hormone therapy that contains the estrogen estradiol valerate and the progestin cyproterone acetate. It is used in hormone replacement therapy for transgender women, and in the treatment of menopausal symptoms, prostate cancer, and certain types of breast cancer.

Etymology

The term "estradiol" is derived from estra-, which is a prefix that refers to the estrane steroid structure, and -diol, a chemical term and suffix indicating that the compound contains two alcohol groups. The term "valerate" refers to the valeric acid ester group that is attached to the estradiol molecule. "Cyproterone" is derived from the chemical structure of the compound, which is a derivative of progesterone.

Pharmacology

Estradiol valerate/cyproterone acetate works by replacing the body's natural hormones. Estradiol valerate is converted in the body to estradiol, the main sex hormone in women, which helps to regulate many processes in the body. Cyproterone acetate is a progestin with anti-androgenic properties. It works by blocking the effects of androgens (male hormones) in the body.

Uses

Estradiol valerate/cyproterone acetate is used in hormone replacement therapy for transgender women. It is also used in the treatment of menopausal symptoms, prostate cancer, and certain types of breast cancer.

Side effects

Common side effects of estradiol valerate/cyproterone acetate include nausea, vomiting, headache, breast tenderness, weight gain, and changes in menstrual periods. Serious side effects may include blood clots, stroke, and heart attack.

See also

• Estradiol
• Cyproterone acetate
• Hormone replacement therapy
• Transgender hormone therapy

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