Estrogen dominance

From WikiMD's Wellness Encyclopedia

Estrogen Dominance is a term used to describe a condition where there is a perceived or actual imbalance between the levels of estrogen and progesterone in the body, with estrogen being in excess. This imbalance is thought to contribute to a variety of health issues and symptoms, particularly in women, although it can also affect men.

Causes[edit | edit source]

Estrogen dominance can be caused by a variety of factors including:

  • Excessive production of estrogen by the body.
  • Reduced levels of progesterone, making estrogen more dominant.
  • Exposure to xenoestrogens, which are environmental estrogens found in certain plastics, pesticides, and personal care products.
  • Obesity, since fat cells produce estrogen.
  • Impaired liver function, which can hinder the body's ability to break down estrogen.
  • Certain medications that can increase estrogen levels.

Symptoms[edit | edit source]

Symptoms of estrogen dominance can vary widely but may include:

  • Menstrual irregularities such as heavy periods or light periods.
  • Mood swings, anxiety, and depression.
  • Weight gain, particularly around the abdomen and hips.
  • Fatigue.
  • Breast tenderness.
  • Fibrocystic breasts.
  • Uterine fibroids.
  • Endometriosis.

Diagnosis[edit | edit source]

Diagnosis of estrogen dominance involves a detailed medical history, physical examination, and laboratory tests to measure hormone levels. These tests may include blood, saliva, or urine testing to evaluate the levels of estrogen and progesterone, as well as other relevant hormones.

Treatment[edit | edit source]

Treatment for estrogen dominance may involve:

  • Lifestyle changes, including diet, exercise, and stress management.
  • Avoiding exposure to xenoestrogens.
  • Use of bioidentical hormones to balance estrogen and progesterone levels.
  • Supplements such as vitamin B6, magnesium, and DIM (Diindolylmethane) to support hormone metabolism and detoxification.
  • Medications to regulate hormone levels, under the guidance of a healthcare provider.

Prevention[edit | edit source]

Preventive measures for estrogen dominance include maintaining a healthy weight, eating a balanced diet rich in fiber and cruciferous vegetables, regular exercise, managing stress, and avoiding known sources of xenoestrogens.


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Contributors: Prab R. Tumpati, MD