Ethinylestradiol/levonorgestrel/bisglycinate

Ethinylestradiol/levonorgestrel/bisglycinate is a combination drug used in oral contraceptives. It combines ethinylestradiol, a synthetic form of the hormone estrogen, with levonorgestrel, a synthetic form of the hormone progesterone, and bisglycinate, which is intended to enhance the bioavailability of the other active ingredients. This medication is primarily used for the prevention of pregnancy. It works by preventing ovulation, thickening the mucus in the cervix to prevent sperm from reaching an egg, and changing the lining of the uterus to prevent attachment of a fertilized egg.

Composition

The medication consists of three main components:

• Ethinylestradiol: A synthetic version of estrogen, it is responsible for controlling the development and maintenance of female sexual characteristics, as well as playing a role in the menstrual cycle.
• Levonorgestrel: A synthetic progestogen, it provides contraceptive effects by preventing ovulation and creating an inhospitable environment for sperm.
• Bisglycinate: Added to improve the absorption and effectiveness of the other two components.

Usage

Ethinylestradiol/levonorgestrel/bisglycinate is taken orally, typically in the form of a pill. The regimen for taking this contraceptive usually follows a specific cycle, such as 21 days on the medication followed by a 7-day break during which menstruation occurs, although instructions can vary depending on the specific product.

Side Effects

Common side effects include nausea, headache, breast tenderness, and mood changes. Serious side effects may include increased risk of blood clots, stroke, and heart attack, especially in smokers and women over 35.

Contraindications

This medication should not be used by individuals who have a history of blood clot disorders, certain types of cancer, unexplained vaginal bleeding, or who are pregnant. It is also contraindicated in individuals who have had severe liver disease or a history of stroke or heart attack.

Interactions

Ethinylestradiol/levonorgestrel/bisglycinate can interact with other medications, reducing its effectiveness or increasing the risk of adverse effects. These include certain antibiotics, anticonvulsants, and herbal supplements like St. John's Wort.

See Also

• Oral contraceptive pill
• Hormonal contraception
• Estrogen
• Progesterone