Ethyleneimine
Synonyms[edit source]
Ethyleneimine, AZIRIDINE, Aminoethylene, Azacyclopropane, Azirane, Aziridine, Dimethyleneimine, Dimethylenimine, Ethylenimine, Ethylimine
Thesaurus
A monofunctional alkylating agent with potential antineoplastic activity. Reacting with DNA mainly at guanine and adenine residues, ethylenimine alkylates DNA, thereby producing DNA interstrand crosslinks and DNA breaks, and interfering with DNA replication and cell division. (NCI04), Organic Chemical, Pharmacologic Substance
- NCI Thesaurus (external)
C292.
This concise article on Ethyleneimine incorporates public domain text from the US National Library of Medicine.
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Contributors: Prab R. Tumpati, MD
